In conjunction with the University of California, Irvine we have received a 5 years NIH award to study aging in our model of senescence the Octodon degus

Publications in 2021

Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice.
‍Hurley MJ, Deacon RMJ, Chan AWE, Baker D, Selwood DL, Cogram P.
‍Brain. 2021.
doi: 10.1093/brain/awab246.

Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy.
‍Reyes ST, Deacon RMJ, Guo SG, Altimiras FJ, Castillo JB, van der Wildt B, Morales AP, Park JH, Klamer D, Rosenberg J, Oberman LM, Rebowe N, Sprouse J, Missling CU, McCurdy CR, Cogram P, Kaufmann WE, Chin FT.
Sci Rep. 2021
doi: 10.1038/s41598-021-94079-7.

Altered Gut Microbiota in a Fragile X Syndrome Mouse Model.
Altimiras F, Garcia JA, Palacios-García I, Hurley MJ, Deacon R, González B, Cogram P.
‍Front Neurosci. 2021.
doi: 10.3389/fnins.2021.653120.

Altered Gut Microbiota in a Fragile X Syndrome Mouse Model.
Cogram P, Alkon DL, Crockford D, Deacon RMJ, Hurley MJ, Altimiras F, Sun MK, Tranfaglia M.
Sci Rep. 2020.
doi: 10.1038/s41598-020-74848-6.PMID: 33093534